Vendor source

Reviewed 2 Oct 2026

Completeness Comprehensive (83%)

BoneXpert

Visiana

BoneXpert analyses an X-ray of a child's hand automatically, without any interference from a human. The main result is the Greulich Pyle bone age - TW2/3 bone ages can also be given. BoneXpert also reports the bone age standard deviation score. The X-ray can be of a left or a right hand and the hand can assume any rotation in the image plane. The analysis is automatically rejected, if it cannot be done reliably, e.g. if there is too much image postprocessing. Finally, the Bone Heath Index is determined from the cortical thicknesses in the metacarpals.

Supported by 23 papers

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Key Features

  • Bone age
  • Bone Health Index
  • Percent Adult Height

General Information

Product name

BoneXpert

Company

Modality

X-ray

Main task

Not specified

Subspeciality

MSK

Disease targeted

Short stature, tall stature, early or late puberty, Congenital Adrenal Hyperplasia (CAH), orthopedic treatment planning, orthodontics, sports medicine, legal medicine, clinical trials

Regulatory Information

CE Certification

Pathway:

MDD

Class:

Class I

Verified by Health AI Register

FDA Certification

Pathway:

510(k) cleared

Class:

Class II

FDA Number:

Verified by Health AI Register

Other certifications

Not specified

Evidence & Research

Peer-Reviewed Papers

Quantifying human variability in pediatric bone age assessment: a multi-institutional multi-reader study and benchmark for AI evaluation

Pediatric Radiology · Sep 2026

Automatic bone age assessment for adult height prediction in children with congenital adrenal hyperplasia

Journal of Pediatric Endocrinology and Metabolism · May 2026

Comparative study of the performance of two versions of the same AI tool for pediatric skeletal maturation assessment

European Radiology · Jan 2026

Bone Health Index (BoneXpert) and parameters of peripheral quantitative computed tomography indicate overall adequate bone health in adolescents with chronic endocrine diseases at time of transition

PLOS One · Dec 2025

Hand X-ray metrics for assessing bone health and fracture risk in Duchenne muscular dystrophy: a cross-sectional study

European Journal of Pediatrics · Nov 2025

Automated bone age calculation is an independent predictor of vertebral fracture burden in Duchenne muscular dystrophy

Osteoporosis International · Oct 2025

Comparative analysis of an automated bone age tool with manual assessment in a multiethnic Southeast Asian paediatric cohort in Singapore

Pediatric Radiology · Aug 2025

Cortical bone status and its determinants in pediatric Klinefelter syndrome

Endocrine Connections · Aug 2025

Comparison of bone age assessment using manual Greulich and Pyle method versus automated BoneXpert method in South African children

South African Journal of Radiology · Apr 2025

Automatic Bone Age Determination in Adult Height Prediction for Girls with Early Variants Puberty and Precoccious Puberty

Journal of Clinical Research in Pediatric Endocrinology · Feb 2025

A comparison of two artificial intelligence-based methods for assessing bone age in Turkish children: BoneXpert and VUNO Med-Bone Age

Diagnostic and Interventional Radiology · Sep 2024

Performance of two different artificial intelligence (AI) methods for assessing carpal bone age compared to the standard Greulich and Pyle method

La radiologia medica · Aug 2024

Comparison of Commercial AI Software Performance for Radiograph Lung Nodule Detection and Bone Age Prediction

Radiology · Jan 2024

Accuracy and self-validation of automated bone age determination

Scientific Reports · Apr 2022

Autonomous artificial intelligence in pediatric radiology: the use and perception of BoneXpert for bone age assessment

Pediatric Radiology · Feb 2022

Automated determination of bone age from hand X-rays at the end of puberty and its applicability for age estimation

International Journal of Legal Medicine · Oct 2016

Validation of automatic bone age determination in children with congenital adrenal hyperplasia

Pediatric Radiology · Oct 2013

Validation of automatic bone age rating in children with precocious and early puberty

Journal of Pediatric Endocrinology and Metabolism · Nov 2011

Validation and Reference Values of Automated Bone Age Determination for Four Ethnicities

Academic Radiology · Aug 2010

A paediatric bone index derived by automated radiogrammetry

Osteoporosis International · Nov 2009

Prediction of Adult Height Based on Automated Determination of Bone Age

The Journal of Clinical Endocrinology & Metabolism · Nov 2009

An Automated Method for Determination of Bone Age

The Journal of Clinical Endocrinology & Metabolism · Apr 2009

Clinical application of automated Greulich-Pyle bone age determination in children with short stature

Pediatric Radiology · Mar 2009

Technical Specifications

Patient population age

Not specified

Input

Posterior anterior (PA) hand radiograph

Input format

DICOM

Output

Annotated DICOM image, DICOM-encapsulated pdf report, Structured Report

Output format

DICOM

Integration

Integration in standard reading environment (PACS), Integration RIS (Radiological Information System), Stand-alone third party application, Support for RIS integration with DICOM Structured Reports

Deployment

Locally on dedicated hardware, Locally virtualized (virtual machine, Docker)

Trigger for analysis

Automatically, right after the image acquisition, On demand, triggered by a user through e.g. a button click, image upload

Processing time

< 10 seconds

Population

Children from age 0 (zero) years, all ethnicities

Market Presence

On market since

03-2009

AI Platforms

Resellers

Not specified

Countries present

>40

Paying clinical customers

>200

Research/test users

13

Pricing Information

Pricing model

Subscription

Based on

Number of analyses

Source: Vendor | First published: Sep 4, 2024 | Last updated: Oct 2, 2026

BoneXpert - Visiana