Vendor source

Reviewed 11 May 2026

Completeness Strong (75%)

mdbrain

mediaire

mdbrain enables AI-powered evaluations of brain MRIs. Currently available modules are Brain Volumetry, Lesion Characterization, Aneurysm Detection, and Tumor Differentiation. As output radiologists receive quantitative reports as well as visual overlays directly into the PACS.

Supported by 13 papers

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Key Features

  • Aneurysm detection with longitudinal follow-up
  • Including hippocampus and ventricles) with longitudinal follow-up
  • Lesion detection including anatomical localization (magnims criteria) and longitudinal follow-up
  • Quantification of brain volume and white/gray matter (global and regional
  • Segmentation of brain regions
  • Tumor differentiation through delineation and quantification of tumor core and surrounding oedema incl. longitudinal follow-up

General Information

Product name

mdbrain

Company

Modality

MR

Main task

Not specified

Subspeciality

Neuro

Disease targeted

Dementia, Multiple Sclerosis (MS), MSA/CBD/PSA, aneurysm, glioma, glioblastoma

Regulatory Information

CE Certification

Pathway:

MDR

Class:

Class IIb

Verified by Health AI Register

Other certifications

Not specified

Evidence & Research

Peer-Reviewed Papers

Artificial Intelligence analysis of lesion dynamics and brain volume in patients with multiple sclerosis

Multiple Sclerosis and Related Disorders · Jan 2026

Integrated Biomarker–Volumetric Profiling Defines Neurodegenerative Subtypes and Predicts Neuroaxonal Injury in Multiple Sclerosis Based on Bayesian and Machine Learning Analyses

Biomedicines · Dec 2025

Prospective clinical evaluation of automatic lesion assessment in patients with multiple sclerosis

Neuroradiology · Nov 2025

Automation bias in AI-assisted detection of cerebral aneurysms on time-of-flight MR angiography

La radiologia medica · Feb 2025

AI-based assessment of longitudinal multiple sclerosis MRI: Strengths and weaknesses in clinical practice

European Journal of Radiology · Jan 2025

Artificial intelligence–based rapid brain volumetry substantially improves differential diagnosis in dementia

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring · Dec 2024

Artificial intelligence can help detecting incidental intracranial aneurysm on routine brain MRI using TOF MRA data sets and improve the time required for analysis of these images

Neuroradiology · Sep 2024

AI supported detection of cerebral multiple sclerosis lesions decreases radiologic reporting times

European Journal of Radiology · Jul 2024

Changes in MRI Workflow of Multiple Sclerosis after Introduction of an AI-Software: A Qualitative Study

Healthcare · May 2024

External evaluation of a deep learning-based approach for automated brain volumetry in patients with huntington’s disease

Scientific Reports · Apr 2024

Impact of an AI software on the diagnostic performance and reading time for the detection of cerebral aneurysms on time of flight MR-angiography

Neuroradiology · Apr 2024

Automated Detection of Cerebral Aneurysms on TOF-MRA Using a Deep Learning Approach: An External Validation Study

American Journal of Neuroradiology · Nov 2022

Triplanar U-Net with lesion-wise voting for the segmentation of new lesions on longitudinal MRI studies

Frontiers in Neuroscience · Aug 2022

Technical Specifications

Patient population age

Not specified

Input

1.5 or 3T MR. Brain volumetry: 3D-T1-MPRage, 1.0 x 1.0 mm²; Lesion characterization: (3D-)T1 and 3D-T2-FLAIR, 1.0 x 1.0 mm²; Aneurysm detection: TOF, 1.0 x 1.0 mm²; Tumor differentiation: 3D-T1, 3D-T2-FLAIR, 1.0 x 1.0 mm², T1 with contrast agent, 3.0 x 3.0 mm², and T2 spin-echo, 3.0 x 3.0 mm²

Input format

DICOM

Output

Structured PDF report including: diagnostically relevant slices from the current exam, tables with quantitative metrics from the current exam (and comparison with previous exam), diagrams with color-coded deviations from norm values. Color-coded segmentation overlays (static + longitudinal).

Output format

Browser-based platform, CSV-Export file, DICOM-PDF, PDF

Integration

Integration in standard reading environment (PACS), Integration RIS (Radiological Information System), Integration via AI marketplace or distribution platform, Stand-alone third party application

Deployment

Cloud-based, Locally on dedicated hardware, Locally virtualized (virtual machine, Docker)

Trigger for analysis

Automatically, right after the image acquisition, On demand, triggered by a user through e.g. a button click, image upload

Processing time

1 - 10 minutes

Population

Early diagnostics and follow up of neurological and neurodegenerative diseases

Market Presence

On market since

01-2019

AI Platforms

Resellers

Angionautix, Bender, Medavis, Medecon, Sanova, Supermedical, Tatramed

Countries present

11 (Germany, Switzerland, Austria, Spain, Portugal, Italy, Romania, Czech Republic, Slovakia, UAE, Israel)

Paying clinical customers

Not specified

Research/test users

Not specified

Pricing Information

Pricing model

Subscription

Based on

Number of analyses

Source: Vendor | First published: May 2, 2024 | Last updated: May 11, 2026