AI-First Workflow Shows Perifissural Nodules Have Negligible Impact in Lung Screening

AI-First Workflow Shows Perifissural Nodules Have Negligible Impact in Lung Screening

Negligible impact of perifissural nodules in an AI-first reader workflow from UK lung screening trial

European Radiology, 2026

Abstract

Introduction: This study examines the impact of perifissural nodules within an AI-first reader workflow in lung cancer screening.

Methods: Research conducted as part of a UK lung screening trial using CT imaging and AI analysis tools.

Results: Findings demonstrate negligible impact of perifissural nodules when using AI-first reader workflow, supporting the clinical utility of AI in lung screening programs.

Conclusion: The study concludes that AI-first workflows effectively handle perifissural nodules with minimal impact on screening outcomes, validating AI integration in clinical practice.

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