Negligible impact of perifissural nodules in an AI-first reader workflow from UK lung screening trial
European Radiology, 2026
Abstract
Introduction: This study examines the impact of perifissural nodules within an AI-first reader workflow in lung cancer screening.
Methods: Research conducted as part of a UK lung screening trial using CT imaging and AI analysis tools.
Results: Findings demonstrate negligible impact of perifissural nodules when using AI-first reader workflow, supporting the clinical utility of AI in lung screening programs.
Conclusion: The study concludes that AI-first workflows effectively handle perifissural nodules with minimal impact on screening outcomes, validating AI integration in clinical practice.

