icobrain ep

icobrain ep helps physicians with the detection of hippocampal sclerosis in patients with intractable (uncontrollable) epilepsy.

The icobrain ep software aids the assessment of hippocampal asymmetry and, therefore, aids the detection of hippocampal sclerosis, a common cause of intractable epilepsy.

icobrain ep uncovers abnormality patterns by:
Comparing hippocampal asymmetry to an age-and-sex matched normative healthy population.
Assessing the juxtacortical abnormalities (which can indicate cortical malformations).
Information source: Vendor
Last updated: March 17, 2024

General Information

Product name icobrain ep
Company icometrix
Subspeciality Neuro
Modality MR
Disease targeted Intractable epilepsy
Key-features Volume quantification, asymmetry index, report generation
Suggested use During: perception aid (prompting all abnormalities/results/heatmaps), report suggestion

Technical Specifications

Data characteristics
Population Intractable epilepsy patients
Input 3D T1 weighted image and 3D FLAIR
Input format DICOM
Output Color-coded segmentation overlays, concise reports with reference statistics.
Output format DICOM
Integration Integration in standard reading environment (PACS), Integration RIS (Radiological Information System), Integration via AI marketplace or distribution platform
Deployment Cloud-based
Trigger for analysis Automatically, right after the image acquisition, On demand, triggered by a user through e.g. a button click, image upload, etc.
Processing time > 10 minutes


Certified, Class I , MDR
FDA 510(k) cleared , Class II
Intended Use Statements
Intended use (according to CE) icobrain mr is intended for automatic labeling, visualization and volumetric quantification of segmentable brain structures from a set of MR images. This software is intended to automate the current manual process of identifying, labeling and quantifying the volume of segmentable brain structures identified on MR images. icobrain mr consists of two distinct image processing pipelines: icobrain mr cross and icobrain mr long. icobrain mr cross is intended to provide volumes from images acquired at a single timepoint. icobrain mr long is intended to provide changes in volumes between two images that were acquired on the same scanner, with the same image acquisition protocol and with same contrast at two different timepoints. The results of icobrain mr cross cannot be compared with the results of icobrain mr long.


Market presence
On market since 02-2020
Distribution channels Blackford, GE Edison marketplace, Nuance PIN
Countries present (clinical, non-research use) 23
Paying clinical customers (institutes) >100
Research/test users (institutes) >300
Pricing model Subscription
Based on Number of analyses


Peer reviewed papers on performance
Non-peer reviewed papers on performance
Other relevant papers