BoneMRI

MRIguidance

BoneMRI is a radiation-free software solution that generates a 3D CT-like (synthetic CT) image to visualize bone structures derived from an MRI scan. It is ideal to assist the diagnosis, monitoring and surgical planning and navigation of orthopaedic conditions. It is available for the Lumbar Spine, Cervical Spine and Pelvic Region.

Information source: Vendor
Last updated: May 2, 2024

General Information

General
Product name	BoneMRI
Company	MRIguidance
Subspeciality	MSK
Modality	MR
Disease targeted	Conditions involving the bony anatomy, such as radiculopathy, osteoarthritis, hip dysplasia, femoral acetabular impingement and spondyloarthritis, degenerative spine disease, spondylolisthesis, spondylosis and spinal fractures
Key-features	Radiation-free bone visualisation from MRI data
Suggested use	Visualize the latent bone structures in MRI images that may be used to assist the diagnosis, monitoring and treatment planning of orthopedic conditions in adult patients by imaging experts.

Technical Specifications

Data characteristics
Population	Patients from 12 years and older suspected of having conditions involving the bony anatomy of the lumbar spine, cervical spine or pelvic region.
Input	3D MR protocol, gradient echo, multi echo, dual echo
Input format	DICOM
Output	Synthetic CT (sCT) in Hounsfield Units, 3D
Output format	DICOM
Technology
Integration	Integration in standard reading environment (PACS)
Deployment	Locally on dedicated hardware, Cloud-based, Hybrid solution
Trigger for analysis	Automatically, right after the image acquisition
Processing time	> 10 minutes

Regulatory

Certification
CE	Certified, Class IIa , MDR
FDA	510(k) cleared , Class II
Intended Use Statements
Intended use (according to CE)	BoneMRI is an image processing software that can be used for image enhancement in MRI images. It can be used to visualise the bone structures in MRI images with increased contrast with respect to the surrounding soft tissue, and may be used to assist the diagnosis, monitoring and treatment planning of orthopaedic conditions by imaging experts. It can be used to visualise T1w contrast. It is to be used in the pelvic region, which includes the bony anatomy of the sacrum, hip bones and femoral heads; and the spine, which includes the bony anatomy of the cervical, thoracic, lumbar, and S1 vertebrae. BoneMRI can be used in patients 12 years and older.

Market

Market presence
On market since	04-2019
Distribution channels	Siemens Syngo.Via
Countries present (clinical, non-research use)
Paying clinical customers (institutes)
Research/test users (institutes)
Pricing
Pricing model	Subscription
Based on	Number of installations

Evidence

Evidence
Peer reviewed papers on performance	MRI-based synthetic CT for assessment of the bony elements of the sacroiliac joints in children (read) MRI-based synthetic CT: a new method for structural damage assessment in the spine in patients with axial spondyloarthritis – a comparison with low-dose CT and radiography (read) Morphometric and clinical comparison of MRI-based synthetic CT to conventional CT of the hip in children (read) MRI-based synthetic CT of the lumbar spine: Geometric measurements for surgery planning in comparison with CT (read) Magnetic resonance imaging-based synthetic computed tomography of the lumbar spine for surgical planning: a clinical proof-of-concept (read) MRI-based synthetic CT shows equivalence to conventional CT for the morphological assessment of the hip joint (read) MRI-based synthetic CT of the hip: can it be an alternative to conventional CT in the evaluation of osseous morphology? (read) MRI-based Synthetic CT in the Detection of Structural Lesions in Patients with Suspected Sacroiliitis: Comparison with MRI (read) Bone visualization of the cervical spine with deep learning-based synthetic CT compared to conventional CT: A single-center noninferiority study on image quality (read)
Non-peer reviewed papers on performance
Other relevant papers	Anatomical variation of the sacroiliac joints: an MRI study with synthetic CT images (read) Common incidental findings on sacroiliac joint MRI: Added value of MRI-based synthetic CT (read) MRI AI Use Case: Synthetic CT Images for Fracture Evaluation (read)